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In the 1330s, a large number of natural disasters and plagues led to widespread famine, starting in 1331, with a deadly plague arriving soon after.

Plague was reportedly first introduced to Europe via Genoese traders at the port city of Kaffa in the Crimea in 1347.

Modern researchers do not think that the plague ever became endemic in Europe or its rat population.

The disease repeatedly wiped out the rodent carriers so that the fleas died out until a new outbreak from Central Asia repeated the process.

Snacking on guacamole may improve your heart health and reduce your risk of developing cancer.

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